Table 3.

Overview of the combined gene and cell therapy based treatment strategies for inflammatory bowel diseases as discussed in this review

	Applied strategy	Viral vector used	Reference for viral vector used	Status of development	Reference for status of development
Combined gene and cell therapy	Ex vivo generated Treg/Tr1	Retrovirus	[113,115]	Preclinical	[113,115]
	T cell receptor transgenic Treg	Retrovirus	[116]	Preclinical	[116]

The status of development refers to research which has already been performed. Treg: CD4⁺CD25^highFOXP3⁺ regulatory T cell; Tr1: Type 1 regulatory T cell.