Table 3.
Histological follow-up studies of gastric intraepithelial neoplasia through mild to severe dysplasia
| Reports (yr) | LGIN (including mild to moderate dysplasia) | HGIN (including severe dysplasia) | ||
| Detection of carcinoma n (%) | Interval (mean) n (%) | Detection of carcinoma | Interval (mean) | |
| Saraga et al[49], 1987 | 1/64 (2) | 4 yr | 17/21 (81) | 4 mo |
| Lansdown et al[46], 1990 | 0/7 (0) | - | 11/13 (85) | 5 mo |
| Rugge et al[50], 1991 | 12/69 (17) | 1 yr | 6/8 (75) | 4 mo |
| Fertitta et al[51], 1993 | 7/30 (23) | 10 mo | 25/31 (81) | 5 mo |
| Farinati et al[52], 1993 | - | - | 16/49 (33)1 | - |
| Di Gregorio et al[53], 1993 | 6/89 (7) | 2 yr | 6/10 (60) | 11 mo |
| Bearzi et al[54], 1994 | 8/81 (9.9) | - | 27/44 (61) | - |
| Rugge et al[55], 1994 | 13/90 (14) | 2 yr | 14/18 (78) | 9 mo |
| Kolodziejczyk et al[56], 1994 | 2/351 (5.72) | - | 7/7 (100) | - |
| Kokkola et al[57], 1996 | 0/9 (0) | - | 2/3 (67) | 1.5 yr |
| Rugge et al[19], 2003 | 8/90 (8.9) | 4 yr | 11/16 (69) | 34 mo |
| Yamada et al[58], 2004 | 0/38 (0) | - | 1/10 (10) | 54 mo |
| Park et al[59], 2008 | 3/26 (12) | 58 mo3 | 1/1 (100) | 58 mo3 |
| Overall | 60/628 (9.5) | 145/231 (63) | ||
Proportion progressing to carcinoma and mean interval.
1
Moderate or severe;
2
Mild or moderate dysplasia;
3
Overall follow-up interval. LGIN: Low-grade intraepithelial neoplasia; IN: Intraepithelial neoplasia; HGIN: High-grade intraepithelial neoplasia.