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. 2011 Nov 4;3:1369–1380. doi: 10.1093/gbe/evr115

Table 3.

Duplication Status per Gene Family Split by Functional Annotation

Duplication versus Fluxa Duplicationb
Function n rc P Zd P
Cell organization and biogenesis 29 0.209 0.274 1.010 0.312
Developmental processes 20 −0.132 0.578 1.693 0.090
DNA or RNA binding or metabolism 26 0.760 <0.0001 −2.284 0.022
Electron transport 7 0.860 0.013 0.460 0.645
Hydrolase activity 114 0.310 <0.001 −1.661 0.097
Kinase activity 62 −0.031 0.817 1.167 0.243
Nucleic acid or Nucleotide binding 94 0.062 0.554 0.011 0.991
Protein binding or metabolism 121 0.139 0.128 1.463 0.143
Signal transduction 13 0.104 0.735 2.450 0.014
Stimulus or stress response 199 0.302 <0.0001 2.650 0.008
Transferase activity 166 0.211 0.006 −0.833 0.405
Transporters or transport 56 −0.034 0.801 1.755 0.079

Bold values are significant at a Bonferroni corrected α = 0.0042.

a

Duplications per gene family versus the maximum flux.

b

Wilcoxon rank test of difference across compartments (positive values: overduplication; negative values: underduplication).

c

Spearman's r, calculated in SAS (v9.2.2, Cary, NC).

d

Wilcoxon's Z, calculated in SAS (v9.2.2, Cary, NC).