Table 3.

Duplication Status per Gene Family Split by Functional Annotation

		Duplication versus Fluxa		Duplicationb
Function	n	rc	P	Zd	P
Cell organization and biogenesis	29	0.209	0.274	1.010	0.312
Developmental processes	20	−0.132	0.578	1.693	0.090
DNA or RNA binding or metabolism	26	0.760	<0.0001	−2.284	0.022
Electron transport	7	0.860	0.013	0.460	0.645
Hydrolase activity	114	0.310	<0.001	−1.661	0.097
Kinase activity	62	−0.031	0.817	1.167	0.243
Nucleic acid or Nucleotide binding	94	0.062	0.554	0.011	0.991
Protein binding or metabolism	121	0.139	0.128	1.463	0.143
Signal transduction	13	0.104	0.735	2.450	0.014
Stimulus or stress response	199	0.302	<0.0001	2.650	0.008
Transferase activity	166	0.211	0.006	−0.833	0.405
Transporters or transport	56	−0.034	0.801	1.755	0.079

Bold values are significant at a Bonferroni corrected α = 0.0042.

^aDuplications per gene family versus the maximum flux.

^bWilcoxon rank test of difference across compartments (positive values: overduplication; negative values: underduplication).

^cSpearman's r, calculated in SAS (v9.2.2, Cary, NC).

^dWilcoxon's Z, calculated in SAS (v9.2.2, Cary, NC).