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Time course of biomass concentration (A), huIFN α2b production (B), residual oleic acid concentration (C) and oleic acid to biomass ratio (D) for the various strategies tested during the induction phase. St 1, St 2, St 3 and St 4 correspond to a 20 g L-1 oleic acid pulse, a 10 g L-1 oleic acid pulse, 4 pulses of oleic acid, at 5 g L-1 at 6 h intervals each, and continuous feeding with oleic acid at a rate of 1.25 g h-1.
