Figure 3.
(a) Typical iodide efflux traces for 1 (black line), 11 (dark-gray), and DMSO control (light-gray). Cells were activated with forskolin at 120 s (arrow i), treated with compound at 500 s (arrow ii), and completely lysed at 800 s (arrow iii). (b) Potentiating effects of all compounds tested (measured as the maximum slope of the iodide efflux trace prior to addition of the compound, subtracted from the maximum slope post addition).