Table 1.
Anakinra n = 10 | Etanercept n = 15 | |||||
---|---|---|---|---|---|---|
Week 0 | Week 12 | P-value | Week 0 | Week 12 | P-value | |
TJC28 | 9.5 (3 to 19) | 7 (1 to 13) | 0.033 | 11 (1 to 25) | 2 (0 to 28) | 0.004 |
TJC68 | 24.5 (9 to 52) | 13.5 (3 to 35) | 0.015 | 15 (3 to 57) | 3 (0 to 38) | 0.002 |
SJC28 | 8 (1 to 18) | 5 (0 to 8) | 0.032 | 4 (1 to 21) | 1 (0 to 8) | 0.005 |
SJC68 | 20.5 (6 to 27) | 8 (0 to 23) | 0.028 | 9 (3 to 43) | 2 (0 to 16) | 0.007 |
ESR | 18.5 (3 to 79) | 7.5 (2 to 46) | 0.059 | 14 (4 to 91) | 5 (1 to 26) | 0.001 |
CRP | 17 (4 to 70) | 7.5 (0 to 29) | 0.044 | 7 (0 to 42) | 0 (0 to 18) | 0.092 |
d VAS | 66 (27 to 85) | 47 (12 to 70) | 0.051 | 44.5 (5 to 93) | 15 (2 to 56) | 0.002 |
p VAS | 65.5 (21 to 91) | 46.5 (20 to 75) | 0.169 | 50 (22 to 93) | 12 (2 to 66) | 0.001 |
HAQ | 1.25 (0.75 to 2.38) | 1.13 (0.25 to 1.88) | 0.057 | 1.13 (0 to 2.5) | 0.25 (0 to 2.25) | 0.01 |
DAS28 | 5.03 (3.77 to 7.16) | 4.17 (2.35 to 5.98) | 0.022 | 5.26 (3.08 to 6.95) | 2.01 (0.14 to 5.35) | 0.001 |
Median (range). d VAS, disease visual analogue scale; p VAS, pain visual analogue scale.