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. 2011 Dec;189(4):1177–1201. doi: 10.1534/genetics.111.133363

Table 3. Salient features of EGO Complex components.

Protein Size Motifs/domains Potential function
Gtr1 310 aa Ras-family GTPase GTP-bound form activates TORC1
Gtr2 341 aa Ras-family GTPase GDP-bound form activates TORC1
Ego1/Meh1/ Gse2 184 aa N-terminal palmitoylation/myristolationa Vacuolar recruitment
Ego3/Slm4/Nir1/Gse1 162 aa Transmembrane domain, PtdIns(3,5)P2 bindinga Vacuolar recruitment
a

Described in Dubouloz et al. (2005), Hou et al. (2005), and references therein.