Table 4.
Covariates | OR for willingness to participate | |||||
---|---|---|---|---|---|---|
Diet Trial | Hypertension Trial |
Cancer Trial |
||||
OR | (95% Cl) | OR | (95% Cl) | OR | (95% Cl) | |
Race | ||||||
White (ref) | ||||||
African American | 0.8 | 0.5,1.1 | 0.8 | 0.6,1.3 | 0.8 | 0.5,1.2 |
Gender | ||||||
F (ref) | ||||||
M | 0.7 | 0.5, 1.0 | 1.8 | 1.3,2.6 | 1.9 | 1.3,2.8 |
Age | ||||||
< 65 (ref) | ||||||
65–80 | 0.8 | 0.5,1.5 | 0.7 | 0.4,1.2 | N/Ac | N/Ac |
≥ 80 | 0.5 | 0.3,0.98 | 0.5 | 0.2,0.9 | ||
Self rating of health | ||||||
Excellent/Very Good/Good (ref) | ||||||
Fair/Poor | 0.9 | 0.6,1.4 | 0.8 | 0.5,1.2 | 0.6 | 0.4,1.0 |
History of target diseaseb | ||||||
N (ref) | ||||||
Y | 1.6 | 1.03,2.3 | 1.1 | 0.8,1.5 | 1.1 | 0.7,1.8 |
Prior participation in clinical trial | ||||||
No prior participation (ref) | ||||||
Personal participation | 1.8 | 1.2,2.6 | 1.4 | 1.0,2.1 | 1.3 | 0.8,2.3 |
Family/friend participation | 0.9 | 0.5,1.6 | 0.6 | 0.3,1.1 | 1.3 | 0.7,2.4 |
Awareness of Tuskegee Syphilis Study | ||||||
N (ref) | ||||||
Y | 1.6 | 1.1,2.3 | 1.1 | 0.7,1.5 | 1.6 | 1.1,2.3 |
Trust in PCP | ||||||
1st quartile (More trust) (ref) | ||||||
2nd quartile | 0.9 | 0.5,1.4 | 1.1 | 0.7,1.8 | 0.7 | 0.4,1.2 |
3rd quartile | 0.6 | 0.4,1.0 | 0.9 | 0.5,1.4 | 0.7 | 0.4,1.2 |
4th quartile (Least trust) | 0.5 | 0.3,0.8 | 0.6 | 0.3,0.9 | 0.6 | 0.4,1.0 |
Distrust in clinical research | ||||||
N (ref) | ||||||
Y | 2.1 | 0.7,6.1 | 1.0 | 0.3,2.7 | 0.6 | 0.2,1.9 |
Receiving money as payment for your time | ||||||
Less Important (ref) | ||||||
More Important | 1.2 | 0.9,1.8 | 1.6 | 1.1,2.3 | 1.8 | 1.2,2.7 |
Your belief that you will personally benefit from participating in the clinical research trial | ||||||
Less Important (ref) | ||||||
More Important | N/Ac | N/Ac | 1.3 | 0.8,2.1 | 1.7 | 1.04,2.8 |
Your belief that someone else in the future will benefit from your participation in the clinical research trial | ||||||
Less Important (ref) | ||||||
More Important | 2.1 | 0.8,5.3 | 3.9 | 1.1,13.8 | 2.9 | 0.8,10.5 |
Members of the research team are from the same race as you are | ||||||
Less Important (ref) | ||||||
More important | N/Ac | N/Ac | N/Ac | N/Ac | 0.5 | 0.3,0.8 |
Models, adjusted for sociodemographics, health/functional status, patient trust in PCP and clinical research, exposure to clinical research, attitudes about clinical research, and perceived discrimination and awareness of the Tuskegee Syphilis Study.
Target diseases are obesity, hypertension, and cancer for diet, hypertension, and cancer trials, respectively.
N/A denotes those variables that were not significantly related to the outcome (p >0.05) in bivariable analysis and thus were not included in the multivariable model.