Table 1.
Demographic and clinical characteristics of patients enrolled in the study.
| Sepsis | Severe sepsis/shock | p | |
|---|---|---|---|
| Number | 125 | 88 | |
| Male/Female | 69/56 | 43/45 | 0.307 |
| Age (years, mean ± SD) | 62.5 ± 22.2 | 72.5 ± 13.1 | < 0.0001 |
| APACHE II score | 11.52 ± 5.76 | 22.68 ± 8.50 | < 0.0001 |
| Type of infection (n) | p: 0.004 | ||
| Acute pyelonephritis | 56 | 18 | |
| Pneumonia (CAP) | 16 | 20 | |
| Intra-abdominal Infection | 30 | 20 | |
| Bacteremia | 13 | 15 | |
| VAP/HAP | 10 | 15 | |
| Predisposing Factors (n, %) | 0.188 | ||
| Chronic Renal Disease | 15 (12.0) | 12 (13.6) | |
| Chronic Obstructive Pulmonary Disease | 10 (8.0) | 10 (11.4) | |
| Heart Failure | 9 (7.2) | 17 (19.3) | |
| Diabetes mellitus type 2 | 27 (21.6) | 17 (19.3) | |
| Solid tumor malignancy | 5 (4.0) | 7 (7.9) | |
| Isolated pathogens irrespective of source (n, %) | 0.037 | ||
| Escherichia coli | 21 (16.8) | 4 (4.5) | |
| Pseudomonas aeruginosa | 7 (5.6) | 5 (5.7) | |
| Klebsiella pneumoniae | 5 (4) | 9 (10.2) | |
| Acinetobacter baumannii | 2 (1.6) | 7 (7.9) | |
| Other Gram-negatives | 10 (8.0) | 4 (4.5) | |
| Staphylococcus aureus | 2 (1.6) | 2 (2.3) | |
| Other Gram-positive | 2 (1.6) | 2 (2.3) | |
| Death | 10 (8.0) | 49 (55.7) | < 0.0001 |