Table 2. Summary of the screening data received before, during and after the change in eligibility.

	Screening data received before June 2008		Screening data received between June 2008 and local R&D approval		Screening data received after local R&D approval		Total
	n	%	n	%	n	%	n	%
Total patients screened	272	100	79	100	151	100	502	100
Total eligible	21	7.7	6	7.6	21	13.9	48	9.6
Total approached	19	7	6	7.6	18	11.9	43	8.6
Total randomised	2	0.7	2	2.5	0	0	4	0.8
Total refused	17	6.3	4	5.1	18	11.9	39	7.8
Total ineligible	248	91.2	73	92.4	125	82.8	446	88.8
Total unknown eligibility	3	1.1	0	0	5	3.3	8	1.6

Abbreviation: R&D=research and development committee.