Table 1. Patients’ characteristics.
FSS |
Radical surgery
|
||||
---|---|---|---|---|---|
Total | Group A | Group B | Group C | P-value | |
Total | 572 | 74 | 52 | 446 | |
Age | <0.0001 | ||||
⩽40 | 126 | 74 | 52 | 0 | |
>40 | 446 | 0 | 0 | 446 | |
FIGO stage | 0.0291 | ||||
IA | 191 | 36 | 18 | 137 | |
IB | 7 | 1 | 0 | 6 | |
IC | 374 | 37 | 34 | 303 | |
IC(r)*1 | 213 | 21 | 21 | 171 | |
IC(non-r)*2 | 161 | 16 | 13 | 132 | |
Histological type | 0.0002#1 | ||||
Serous | 64 | 4 | 4 | 56 | |
Mucinous | 150 | 43 | 18 | 89 | |
Clear-cell | 212 | 13 | 17 | 182 | |
Endometrioid | 128 | 14 | 11 | 103 | |
Others*3 | 18 | 0 | 2 | 16 | |
Grade | 0.294#2 | ||||
G1/G2 | 323 | 57 | 33 | 233 | |
G3 | 37 | 4 | 2 | 31 | |
NC*4 | 212 | 13 | 17 | 182 | |
Comprehensive surgical staging surgery | NA | ||||
Yes | 321 | NC | 24 | 297 | |
No | 177 | NC | 28 | 149 | |
FSS | 74 | 74 | NC | NC | |
Preoperative CA125 value | 0.0003 | ||||
⩽35 IU ml–1 | 204 | 29 | 14 | 161 | |
>35 IU ml–1 | 332 | 33 | 37 | 262 | |
Unknown | 36 | 12 | 1 | 23 | |
Peritoneal cytology | 0.145 | ||||
Negative | 407 | 58 | 35 | 314 | |
Positive | 165 | 16 | 17 | 132 | |
Platinum-based chemotherapy | 0.266#3 | ||||
Taxane plus platinum | 241 | 22 | 16 | 203 | |
Conventional platinum-based | 205 | 32 | 30 | 143 | |
None | 126 | 20 | 6 | 100 |
Abbreviations: FIGO=International Federation of Gynecology and Obstetrics; FSS=fertility-sparing surgery; NC=not classified; NA=not analysed; *1=intraoperative capsule rupture; *2=washing/ascites positive or preoperative capsule rupture; *3=mixed epithelial tumour and undifferentiated carcinoma; *4=grade of clear-cell pathology was not classified. P-values: comparison of groups A with groups B–C; #1=Clear-cell vs non clear-cell, #2=G1/G2 vs G3; #3=platinum-based chemotherapy, present vs absent.