Figure 1. Antiproliferative effects of ST2782 alone (▪) or in combination with PTX (A) or vinorelbine (C, VIN) or nocodazole (C, NCD) at two indicated concentrations corresponding to IC20 (▾) or IC50 (▴), against ovarian carcinoma cells treated for 72 h.
Similar experiments were performed with the combination of PTX/ST3595 (B) or PTX/SAHA (D). Each point of the dose-response curves is the mean±SD of three independent experiments. Each panel reports the combination index values (CI) calculated according to “Chou Talalay method”.