Skip to main content
. 2011 Nov 3;27(1):61–72. doi: 10.1093/humrep/der362

Figure 2.

Figure 2

The effect of LPS on IL-8 and IL-6 protein expression with or without dexamethasone pretreatment in human EVTs. IL-8 (A) and IL-6 (C) protein expression was measured in EVT cell culture supernatants by ELISA after 24h of incubation with LPS. Pretreatment (2h) with DEX (100 nM) reversed the LPS (1 μg/ml) mediated increase in IL-8 (B) and IL-6 (D) protein expression. DEX alone and ethanol (EtOH) (DEX vehicle control) treatments were also included as negative controls. Each bar represents mean ± SEM. Data in Fig. 2B and D are presented as a percentage of LPS-treated EVT cells. Three independent experiments were performed with cells isolated from three different placentas. *P < 0.05 versus non-treated control, one-way repeated measures analysis of variance (RM ANOVA), #P < 0.001 versus LPS, one-way RM ANOVA, Student–Newman–Keuls (SNK).