Table 2. Influence of different variables on the risk of developing pre-diabetes and diabetes mellitus — ordinal logistic model.
Variable | Before adjustment | After adjustment (Model one) | After adjustment (Model two) | After adjustment (Model three) | After adjustment (Model four) | |||||
OR (95.0% CI) | Sig | OR (95.0% CI) | Sig | OR (95.0% CI) | Sig | OR (95.0% CI) | Sig | OR (95.0% CI) | Sig | |
Age | 0.981 (0.644–1.495) | 0.929 | 0.752 (0.473–1.196) | 0.228 | 0.791 (0.494–1.269) | 0.331 | 0.786 (0.498–1.243) | 0.303 | 0.821 (0.516–1.305) | 0.403 |
Sex | 0.872 (0.553–1.375) | 0.556 | 0.792 (0.481–1.304) | 0.359 | 1.056 (0.633–1.762) | 0.835 | 0.814 (0.498–1.333) | 0.414 | 1.094 (0.662–1.810) | 0.725 |
Hypertension | 1.952 (1.278–2.980) | 0.002 | 1.741 (1.105–2.743) | 0.017 | 1.930 (1.214–3.068) | 0.005 | 1.725 (1.102–2.699) | 0.017 | 1.848 (1.172–2.914) | 0.008 |
WC | 1.554 (1.012–2.384) | 0.044 | 1.219 (0.761–1.954) | 0.410 | 2.347 (1.433–3.845) | 0.001 | - | - | - | - |
WHR | 2.513 (1.519–4.158) | <0.001 | - | - | - | - | - | - | - | - |
BMI | 1.477 (0.974–2.241) | 0.067 | - | - | - | - | 1.062 (0.671–1.680) | 0.797 | 1.966 (1.231–3.140) | 0.005 |
TC | 1.398 (0.855–2.284) | 0.182 | 1.304 (0.766–2.219) | 0.327 | 1.237 (0.721–2.123) | 0.440 | 1.323 (0.775–2.260) | 0.305 | 1.292 (0.752–2.220) | 0.354 |
TG | 1.514 (0.991–2.314) | 0.055 | 1.101 (0.685–1.769) | 0.691 | 1.515 (0.931–2.465) | 0.094 | 1.095 (0.685–1.752) | 0.704 | 1.549 (0.956–2.510) | 0.076 |
Lower HDL-C | 1.026 (0.492–2.138) | 0.945 | - | - | - | - | - | - | - | - |
Higher LDL-C | 1.294 (0.492–3.403) | 0.602 | - | - | - | - | - | - | - | - |
Hyperinsulinemia | 1.179 (0.734–1.893) | 0.497 | - | - | - | - | - | - | - | - |
HOMA-β index | 3.574 (2.177–5.867) | <0.001 | - | - | 6.445 (3.567–11.643) | <0.001 | - | - | 6.035 (3.410–10.682) | <0.001 |
HOMA-IR index | 2.317 (1.323–3.452) | 0.002 | 2.039 (1.179–3.524) | 0.011 | - | - | 2.113 (1.223–3.650) | 0.007 | - | - |
Hs-CRP | 1.030 (1.052–2.686) | 0.030 | 1.446 (0.871–2.403) | 0.154 | 1.222 (0.729–2.050) | 0.447 | 1.443 (0.879–2.368) | 0.147 | 1.290 (0.779–2.134) | 0.322 |
IgE | 1.674 (1.039–2.698) | 0.034 | 1.713 (1.031–2.846) | 0.038 | 1.599 (0.955–2.679) | 0.074 | 1.866 (1.128–3.087) | 0.015 | 1.763 (1.058–2.937) | 0.030 |
Chymase | 1.387 (0.858–2.244) | 0.182 | 1.214 (0.730–2.020) | 0.241 | 1.431 (0.850–2.410) | 0.178 | 1.122 (0.677–1.859) | 0.655 | 1.218 (0.730–2.033) | 0.449 |
Tryptase | 1.283 (0.794–2.074) | 0.309 | 1.357 (0.815–2.260) | 0.454 | 1.210 (0.720–2.033) | 0.472 | 1.238 (0.747–2.051) | 0.407 | 1.071 (0.641–1.789) | 0.795 |
OR: odds ratio; CI: confidence interval; WC: waist circumference; WHR: waist-to-hip ratio; BMI: body-mass index; TC: total cholesterol; TG: triglyceride; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; HOMA: homeostatic model assessment; hs-CRP: high-sensitivity C-reactive protein; IgE: immunoglobulin E.