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. 2011 Dec 16;6(12):e28962. doi: 10.1371/journal.pone.0028962

Table 3. Infuence of interactions between CRP and different variables on the risk of developing pre-diabetes and diabetes mellitus — ordinal logistic model.

Variable Before adjustment After adjustment (Model three)
OR (95.0% CI) Sig OR (95.0% CI) Sig
Age 1.828 (1.027–3.252) 0.040 1.636 (0.909–2.947) 0.101
Sex 1.868 (1.063–3.282) 0.030 1.695 (0.952–3.020) 0.073
Hypertension 2.552 (1.364–4.776) 0.003 2.397 (1.270–4.524) 0.007
WC 2.358 (1.273–4.367) 0.006 2.342 (1.256–4.364) 0.007
WHR 2.690 (1.207–5.998) 0.016 2.631 (1.178–5.876) 0.018
BMI 2.278 (1.202–4.317) 0.012 2.180 (1.135–4.184) 0.019
TC 1.424 (0.583–3.480) 0.438 1.447 (0.589–3.552) 0.420
TG 2.809 (1.335–5.909) 0.006 2.431 (1.118–5.285) 0.025
Lower HDL-C 1.096 (0.302–3.975) 0.889 1.072 (0.295–3.900) 0.916
Higher LDL-C 0.789 (0.185–3.373) 0.750 0.772 (0.180–3.308) 0.727
Hyperinsulinemia 1.829 (0.779–4.296) 0.166 1.550 (0.646–3.718) 0.326
HOMA-β index 4.091 (1.821–9.191) 0.001 4.222 (1.867–9.549) 0.001
HOMA-IR index 2.444 (0.994–6.008) 0.051 2.102 (0.835–5.294) 0.115
IgE 2.204 (1.020–4.759) 0.044 2.251 (1.037–4.885) 0.040
Tryptase 1.853 (0.859–4.000) 0.116 1.698 (0.776–3.713) 0.185
Chymase 2.031 (0.973–4.240) 0.059 1.892 (0.896–3.997) 0.094

OR: odds ratio; CI: confidence interval; WC: waist circumference; WHR: waist-to-hip ratio;

BMI: body-mass index; TC: total cholesterol; TG: triglyceride; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; HOMA: homeostatic model assessment;

IgE: immunoglobulin E.