Table 2. Sequence alignment of wild-type and mouse-adapted seasonal H1N1 A/Brisbane/59/2007 viruses of each passage.
Virus | PB2 | PB1 | PA | HA | NP | NA | M2&M1 | NEP&NS1 | |||||
nt | aa | nt | aa | nt | aa | ||||||||
317 | 89 | 425 | 125 | 713 | 221 | ||||||||
WT | - | - | - | C | Thr | A | Asn | A | Asp | - | - | - | - |
MA-1 | - | - | - | C | Thr | A | Asn | A | Asp | - | - | - | - |
MA-2 | - | - | - | C | Thr | C | Thr | A | Asp | - | - | - | - |
MA-3 | - | - | - | C | Thr | C | Thr | G | Gly | - | - | - | - |
MA-4 | - | - | - | C | Thr | C | Thr | G | Gly | - | - | - | - |
MA-5 | - | - | - | C | Thr | C | Thr | G | Gly | - | - | - | - |
MA-6 | - | - | - | T | Ile | C | Thr | G | Gly | - | - | - | - |
MA-7 | - | - | - | T | Ile | C | Thr | G | Gly | - | - | - | - |
MA-8 | - | - | - | T | Ile | C | Thr | G | Gly | - | - | - | - |
Note: WT, wild-type; MA, mouse-adapted; nt, nucleotide; aa: amino acid.