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. 2011 Dec 16;6(12):e28952. doi: 10.1371/journal.pone.0028952

Table 2. HIV-1 drug resistance in ARV-naïve subjects with primary HIV-1 infection.

2a: OLA versus consensus sequencing of plasma 2b: OLA versus consensus sequencing of PBMC 2c: Consensus sequencing of plasma versus PBMC 2d: OLA of plasma versus PBMC
p = .0005 OLA p = .002 OLA p = 1.0 PBMCs p = 1.0 PBMCs
+ + + +
sequencing 83 12 sequencing 81 13 plasma 94 1 plasma 72 11
+ 0 4 + 1 4 + 0 4 + 10 6

ARV: antiretroviral; OLA: oligonucleotide ligation assay; PBMC: peripheral blood mononuclear cells.

+ = subjects with ≥1 mutation or mixture.

− = subjects without mutations or with indeterminate results.

Numbers represent subjects in whom HIV-1 drug resistance was/was not detected in plasma and PBMC specimens that had been obtained a median of 29 (IQR 19–66) and 31 (IQR 19–66) days after HIV-1 infection, respectively; all specimens were collected within six months of infection. McNemar's exact tests compare only subjects with discordant results (indicated in bold).