Table 3.
Proportional hazard competing risk* of dementia by mid-life systolic blood pressure, treatment status, and age strata: HHP/HAAS
Systolic Blood Pressure (mmHG) | Treated with anti-hypertensive meds
|
Untreated
|
||||||
---|---|---|---|---|---|---|---|---|
<50 yrs old (n=631)
|
≥50 yrs old (n=2602)
|
<50 yrs old (n=688)
|
≥50 yrs old (n=3464)
|
|||||
RR* (95% CI)† | RR* (95% CI)† | RR* (95% CI)† | RR* (95% CI)† | |||||
reference‡ | reference‡ | reference‡ | reference‡ | |||||
Normotensive (<120) | 1.04 | (0.96–1.13) | 0.92 | (0.88–0.98) | 1.02 | (0.95–1.08) | ||
Prehypertension (120 – <140) | 1.12 | (0.90–1.40) | 0.84 | (0.75–0.95) | 1.54 | (1.20–1.96) | 1.03 | (0.90–1.18) |
Hypertension (≥ 140) | 1.19 | (0.85–1.66) | 0.76 | (0.65–0.93) | 2.29 | (1.41–3.61) | 1.05 | (0.86–1.27) |
Adjusted for competing risk of death
1000 bootstrapped 95% CI for all competing risk RR
Reference group (n = 493) includes untreated men with normal blood pressure who are < 50 years of age at baseline in 1965