Fig. 7.
Microbubble perfusion is reduced in two of three sunitinib-treated and one of two vehicle-treated PDAC tumors from Ptf1a-Cre LSL-KrasG12D p53R172H/+ mice, treated for 12 d. (A) Microbubble perfusion in vehicle-treated tumors. (B) Microbubble perfusion in sunitinib-treated tumors. Blue diamonds, microbubble data acquired before the trial (Pre); red squares, microbubble data acquired at the end of the trial (Post). Again, one of two untreated controls showed reductions in blood flow over the 12-d period of continuing tumor growth and progression.