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. Author manuscript; available in PMC: 2013 Jan 1.
Published in final edited form as: Int J Biochem Cell Biol. 2011 Oct 25;44(1):158–169. doi: 10.1016/j.biocel.2011.10.011

Figure 2. ET-1 activation of FAK is inhibited by blockade of either ET-A or ET-B.

Figure 2

Growth-arrested IMR-90 fibroblasts were treated with/without ET-1 (1.0 nM) for 1 hour in the presence/absence of inhibitors of ET-A (BQ123, 10 μM) and/or ET-B (BQ788, 10 μM). (A) Y397 p-FAK was assessed by Western blotting and blots were stripped and probed for total FAK. (B) Densitometric analysis normalized to untreated controls. * p < 0.01 vs. untreated control. # p < 0.01 vs. ET-1 treated cells. n = 4.