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. Author manuscript; available in PMC: 2013 Jan 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2011 Oct 27;32(1):92–102. doi: 10.1161/ATVBAHA.111.238618

Figure 5. Genomic profiling of BMMCs transplanted into ischemic myocardium reveals down-regulation of differentiation and cell fate commitment pathways.

Figure 5

Figure 5

Figure 5

Ball-and-stick figures represent ontological cluster function analysis of gene expression changes. Enumerated spheres represent significantly up- or down-regulated groups of genes (GO-terms). Size of spheres correlates to the significance of enrichment of the GO term (sphere radius is proportional to −log10[p-value for GO-term]) and numbers within sphere designate number of genes within the GO-term significantly up or down-regulated. Solid lines represent parent-daughter relationship between terms; terms related otherwise are connected by dashed lines. Functional groups were further sub-sorted into Molecular Function (A) and Biological Processes (B).