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. Author manuscript; available in PMC: 2012 Aug 1.
Published in final edited form as: Expert Rev Respir Med. 2011 Oct;5(5):683–697. doi: 10.1586/ers.11.51

Table 1.

SV40 transgenic animal models.

Study (year) Sequence Promoter Host Tumor type Ref.
Hanahan (1985) Tag Rat insulin II Mouse Insulinoma [45]
Wikenheiser et al. (1992) Tag Human surfactant protein C Mouse Adenocarcinoma [46]
Maroulakou et al. (1994) Tag, tag Rat prostatic steroid binding protein C3(1) Mouse Adenocarcinoma (only in females) [47]
Greenberg et al. (1995) Tag, tag Rat probasin Mouse Invasive adenocarcinoma (only in males) [48]
Hurwitz (2001) Tag, tag Rat probasin Mouse Invasive adenocarcinoma (only in males) [49]
Santarelli et al. (1996) Tag, tag Mouse whey acidic milk protein Mouse Breast [50]
Perez-Stable et al. (1996) Tag Human fetal IgG γ-globin Mouse Prostate [51]
Garabedian et al. (1997, 1998) Tag Mouse cryptdin-2 Mouse Prostate [52,53]
Asamoto et al. (2001) Tag Rat probasin Rat Prostate carcinoma [54]
Masumori et al. (2001), Gabril et al. (2002) Tag Rat probasin Mouse Adenocarcinoma [55,56]
Gabril et al. (2002) Tag PSP94 Mouse Adenocarcinoma [56]
Hicks et al. (2003) Tag Clara-cell secretory protein 10 Mouse Adenocarcinoma, lung parenchymal [57]
Garson et al. (2003) Tag Ovarian-specific promoter 1 Mouse Ovarian and brain tumors, abdominal and bone sarcoma [58]
Lou et al. (2005) Tag, tag Human antithrombin III gene Mouse Hepatocarcinoma [59]
Grippo et al. (2000) Tag Cytokeratin 19 Mouse Urinary bladder tumors Mesothelioma [60]
Robinson et al. (2006) Tag Mesothelin Mouse Mesothelioma [61]
Köbbert et al. (2008) Tag SM22α Mouse Cardiac rhabdomyosarcoma [62]
ter Brugge et al. (2009) Tag Immunoglobulin heavy chain, opposite orientation Mouse B-cell chronic lymphocytic leukemia [63]
Stahl et al. (2009) Tag inducible Hepatocyte-specific albumin Mouse Hepatocellular carcinoma [64]
Iwakura et al. (2009) Tag Human ghrelin Mouse Ghrelinoma [65]

Tag: Large T antigen; tag: Small t antigen.