Table I.
Performance characteristics of the SHE, BALB/c 3T3 and C3H10T1/2 assays calculated for OECD DRP (8)
| SHE pH 6.7 | SHE pH 7.0 | BALB/c 3T3 | C3H10T1/2 | |
| Concordancea (%) | 74 | 85 | 68 | 84 |
| Sensitivity (%) | 66 | 92 | 75 | 72 |
| Specificity (%) | 85 | 66 | 53 | 80 |
| Positive predictivity | 88 | 88 | 77 | 95 |
| Negative predictivity | 62 | 75 | 50 | 34 |
| False-positive rate | 15 | 34 | 47 | 20 |
| False-negative rate | 33 | 08 | 25 | 28 |
| Number of chemicals | 88 | 204 | 149 | 96 |
| Number of carcinogens (%) | 54 (61) | 142 (74) | 100 (68) | 81 (84) |
a
Concordance = agreement between rodent carcinogenicity and CTA results.