Table I.
Effect of demographic characteristics and hTERT genotype on mean TL in peripheral lymphocytes of study subjects
Variable | Number of subjects | TL (kb)a (group mean ± SD) |
All | 56 | 6.0 ± 1.0 |
Age (years) | ||
≤56b | 23 | 6.5 ± 1.0 |
>56 | 33 | 5.7 ± 0.9** |
Gender | ||
Males | 25 | 5.9 ± 1.0 |
Females | 31 | 6.1 ± 1.0 |
Smoking habits | ||
Current | 9 | 6.4 ± 0.6 |
Ex/never-smokers | 47 | 5.9 ± 1.1 |
hTERT genotype | ||
TT | 18 | 6.2 ± 1.2 |
TC | 28 | 6.0 ± 0.7 |
CC | 10 | 5.5 ± 1.4 |
TL, individual mean telomere length, as determined by TRF analysis (see Methods).
Mean population age.
**P value = 0.005 (non-parametric Mann–Whitney U test).