Table 6.

Results of classification systems for BBB permeability taken from the literature

Method	Validation	Number of descriptors	Dataset size	Overall accuracy	Reference
SVM	10-fold CV	<100	351	83.0	[28]
DT	–	2	43	86.0	[56]
SVM	10-fold CV	8	351	80.0	[28]
SVM	5-fold CV	5	415	79.1	[38]
RF	100 BS	4	202	88.2	This work

SVM support vector machine, DT decision tree, RF random forest, CV cross-validation, BS bootstrapping