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. Author manuscript; available in PMC: 2013 Feb 1.
Published in final edited form as: Biomaterials. 2011 Nov 26;33(5):1607–1617. doi: 10.1016/j.biomaterials.2011.11.011

Figure 4.

Figure 4

a) Effect of control gel and skin penetrating nanogels (SPNs) containing SP and KP treatment on the response of allergic contact dermatitis (ACD) model in C57/BL mice. Data represent mean ± SD, n = 6, significance gel against SPNs where *p < 0.001. b) H&E histological staining of i) inflammation induced by topical application of DNFB, and after 3 days treatmnt of ii) spantide II and ketoprofen comprising gel (SP+KP gel) iii) spantide II and ketoprofen comprising skin penetrating nanogels (SP+KP-SPN) and iv) a positive control, Topgraf® (tacrolimus ointment 0.1%).