Table 2.
IMQ-induced skin inflammation in mice phenotypically resembles psoriasis. C57BL/6 mice were treated daily for 5 days with IMQ suspension on the shaved back skin and then the inflamed area was treated with SP+KP gel, SPNs and Topgraf®. Psoriasis Area and Severity Index (PASI) score of the back skin was recorded daily on a scale from 0 to 4.
Day | Control (No treatment) | SP+KP-gel | KP-SPN | SP-SPN | SP+KP-SPN | Topgraf® |
---|---|---|---|---|---|---|
0 | 4 | 4 | 4 | 4 | 4 | 4 |
1 | 4 | 4 | 4 | 4 | 3 | 1 |
2 | 4 | 4 | 4 | 3 | 3 | 0 |
3 | 4 | 4 | 3 | 3 | 2 | 0 |
4 | 4 | 3 | 3 | 2 | 2 | 0 |
5 | 4 | 3 | 3 | 2 | 1 | 0 |