Table 1.

Regulation of SIRT1 levels via transcription and post-transcriptional modification

Levels	Regulators	Roles	Results	References
Transcription	E2F2	TF	↑	Wang, 2006
	FOXO1	TF	↑	Xiong, 2011
	FOXO3	TF	↑	Nemoto, 2004
	TLX	NR	↑	Iwahara, 2009
	HIC1	TF	↓	Chen, 2005c
	p53	TF	↓	Nemoto, 2004
	PPARγ	NR	↓	Han, 2010
Post- transcription	HuR	RNA-binding proteins	↑	Brennan, 2001; Abdelmohsen, 2007
	miR-9	MicroRNA	↓	Saunders, 2010
	miR-34a	MicroRNA	↓	Yamakuchi, 2008; Lee, 2010
	miR-132	MicroRNA	↓	Strum, 2009
	miR-199a	MicroRNA	↓	Rane, 2009
	miR-217	MicroRNA	↓	Menghini, 2009

Abbreviations: NR, nuclear receptor; TF, transcription factor.