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. 2011 Dec 19;1:201. doi: 10.1038/srep00201

Figure 7. CDDO-TFEA induces early oligodendrocyte maturation.

Figure 7

Total brain cells prepared from P3 rat pups were cultured with vehicle (A–C and G–I) or with 10 nM CDDO-TFEA (D–F and J–L) for 3 days (A, D, G, J), 6 days (B, E, H, K), or 10 days (C, F, I, L). Cells were fixed and immunostained using antibodies against A2B5 to detect immature oligodendrocyte precursor cells (A–F) or against O4 to detect mature oligodendrocytes (G–L). (Scale bar is 100 μm). Quantitative analysis of the percentage of (M) A2B5 or (N) O4 positive cells after different days of CDDO-TFEA treatment is shown. Data are the mean ± SEM. **, P , 0.01, *, P , 0.05, Student's t test.