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. Author manuscript; available in PMC: 2012 Jun 1.
Published in final edited form as: Mol Cancer Ther. 2011 Oct 17;10(12):2373–2383. doi: 10.1158/1535-7163.MCT-11-0326

Figure 2.

Figure 2

ABT-737 is more effective at inducing apoptosis in neuroblastoma cell lines in hypoxia than in normoxia. A. Histograms showing % annexin V positive cells at 18-48 hrs after ABT-737 exposure in all 6 neuroblastoma cell lines in hypoxia and normoxia. B. Representative western blots for HIF-1α, PARP and cleaved caspase 3 in response to 24-72 hr exposure to ABT-737 in varying concentration in normoxia and hypoxia in 4 neuroblastoma cell lines. Actin is shown as a loading control. Blots are representative of 3 independent experiments.