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Comparison of immunochromatographic assay with competitive direct ELISA. Kanamycin was administered intramuscularly to rabbits at 20 mg/kg/day for 3 consecutive days as described in Materials and Methods. Blood samples were collected from rabbits 2, 4, 6, 8, 10, and 12 h after the last injection of kanamycin. Plasma samples were subjected to immunochromatographic assay. Subsequent competitive direct ELISA determined the kanamycin concentration in plasma samples.
