Figure 2. Structure-based relationships of dsDNA virus jelly rolls.

Based on structural superpositions, the dsDNA jelly rolls organize as shown. In each case, the tertiary structure is shown as well as the quaternary structure of the capsids in which they appear. This fold is exceptionally versatile in generating capsids with large pseudo-equivalent surface lattices. Both D13 and the adenovirus subunit are associated with viruses infecting mammalian hosts and they both have elaborate insertions between strands of the jelly rolls compared to the other viruses in this category. However, the largest insertion in D13 is in the C-terminus jelly roll, while the largest insertions in the adenovirus subunit are in the N-terminal jelly roll. The canonical dsDNA fused jelly rolls is shown for STIV with the strands labeled in the established manner.