Figure 4.

Inside-burrow behaviors. Non-threatened mouse behaviors and the effects of intraperitoneal administration of vehicle or cannabidiol (CBD) at 0.3, 3, or 30 mg/kg on the behavioral index (BI) (a) and duration (b) of defensive attention, the BI (c) and duration (d) of risk assessment, the BI (e) and duration (f) of rearing and the BI (g) and duration (h) of grooming exhibited by mice during the confrontation with the wild constrictor snake after a 3-day habituation period in the arena. Columns represent the mean and bars the SEM, n=11–12 mice per group. ^#P<0.05 when compared with the group not submitted to any threatening situation (no-threat). BI=(100 × number of behavioral responses)/(time in seconds spent outside or inside the burrow).