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. Author manuscript; available in PMC: 2011 Dec 19.
Published in final edited form as: Cancer Res. 2010 May 18;70(11):4433–4442. doi: 10.1158/0008-5472.CAN-09-4289

Figure 2. NF-κB inhibition upon long term celecoxib exposure was associated with reduced TLR2 and TLR4 expression, and TAK-1 activity.

Figure 2

IBs examined treatment time-dependent changes in expression of TAK-1 vs. its active isoforms (A). IB analysis is shown of treatment time-dependent changes in TLR2, and TLR4 but not in NOD-2 expression (B, Left). Representative photomicrographs of serial sections of ileum from Min/+ mice treated with celecoxib for 4 days are shown that were immunostained separately for TLR4 and TLR2 (B, Right).