Table 1.
Summary of the effects of α-enolase knockdown on the sensitivity of tumor cells to antitubulin chemotherapeutics
| Cell Line | Vincristine Fold decreases in IC50 | Taxol | |
|---|---|---|---|
| A549 | Lung | 4.2 | 2 |
| H460 | Lung | 2.5 | 3.7 |
| MCF-7 | Breast | 12.9 | 10.9 |
| CaOV3 | Ovarian | 7.8 | 24.6 |
Note: The results show the fold decrease in IC50 values of the tumor cells transfected with α-enolase-siRNA relative to CTL siRNA.