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. 2011 Oct 21;2(4):303–308.

Table 1.

Summary of the effects of α-enolase knockdown on the sensitivity of tumor cells to antitubulin chemotherapeutics

Cell Line Vincristine Fold decreases in IC50 Taxol
A549 Lung 4.2 2
H460 Lung 2.5 3.7
MCF-7 Breast 12.9 10.9
CaOV3 Ovarian 7.8 24.6

Note: The results show the fold decrease in IC50 values of the tumor cells transfected with α-enolase-siRNA relative to CTL siRNA.