Figure 6.
Axonal GABAARs increase somatic excitability. A, Representative EPSC (left) and average EPSC amplitudes (right) before/after (black) or during (red) muscimol application in control ACSF or in the presence of EGTA-AM (20 μm). EPSC were evoked by a bipolar electrode placed in the granule cell layer and recorded in stellate cells. B, Voltage traces from 5 pairs of granule cell somatic depolarization in control conditions (left) or proceeded by GABA iontophoresis on the axon (right). C, Average (bars) and individual cell (connected circles) spike success rates in control conditions and following GABA iontophoresis.