Table 2. Detection of malignant melanoma engraftment.
| % CAG cells detected in BM by FC | FLC (mg l−1 ) detected in serum of CAG xenografted turkey embryos | % ARH-77 cells detected in BM by FC | FLC (mg l−1 ) detected in serum of ARH-77 xenografted turkey embryos |
|---|---|---|---|
| 1.4 | 6.77 | 8.5 | 7.15 |
| 4.7 | 5.85 | 7.2 | 5.56 |
| 10.9 | 6.06 | 6.3 | 9.58 |
| 5.6 | 9.14 | 12.3 | 29.56 |
| 1.5 | <3 | 14.2 | 32.56 |
| 2.6 | <3 | 2.6 | 17.35 |
| 9.6 | 47.2 | 5.6 | 12.85 |
| 5.3 | 18.5 | 13.1 | 7.05 |
| 5.9 | 29.5 | 8.1 | 24.2 |
| 9.3 | 5.39 | 9.1 | <3 |
| 5 | 4.39 | 7.5 | 7.08 |
| 3.9 | 6.08 | 8.2 | <3 |
| 1.3 | 7.09 | 4.3 | 3.09 |
| 5.15±3.18 | 13.27±13.56 | 8.23±3.37 | 14.18±10.27 |
Abbreviations: BM=bone marrow; FC=flow cytometry; FLC=free light chain; MM=multiple myeloma.
MM cells (5 × 106) were injected intravenously on E11 and BM and serum collected 1 week later on E18. Engraftment was detected by FC and values presented are average %±s.d. FLC levels were detected by nephelometry and all control embryos had values below the detection range of <3 mg l−1.