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. 2011 Nov 1;105(11):1708–1718. doi: 10.1038/bjc.2011.445

Table 4. Survival of embryos after treatment with varying concentrations of thalidomide.

Thalidomide concentration Number of turkey embryos injected on E13 Number of turkey embryos that survived by E18
0 (vehicle only 50% PBS+50% ethanol) 6 5
30 μg per embryo 6 0
60 μg per embryo 6 0
120 μg per embryo 6 0
0 (vehicle only 50% PBS+50% ethanol) 6 4
3 μg per embryo 6 0
6 μg per embryo 6 0
12 μg per embryo 6 0
0 (vehicle only 50% PBS+50% ethanol) 6 5
0.3 μg per embryo 6 0
0.6 μg per embryo 6 0
0.12 μg per embryo 6 0

Abbreviation: PBS=phosphate-buffered solution.

The human therapeutic dose is equivalent to 60–120 μg per embryo.