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. 2011 Nov 1;105(11):1708–1718. doi: 10.1038/bjc.2011.445

Table 5. Survival of turkey embryos after treatment with increasing concentrations of bortezomib.

Bortezomib concentration (μg per embryo) Number of turkey embryos treated Number of surviving turkey embryos % Survival
0 5 5 100
0.1 5 4 80
0.2 7 6 87
0.4 8 6 75
0.6 5 3 60
1.2 14 7 50
2.4 15 3 20
3.6 12 0 0

The human therapeutic dose is equivalent to 0.8–1.2 μg per embryo.