Table 2.

Adverse Events During Treatment (n=36)

	Total reported, n (%)	Severe or intolerable, n (%)
Any AEs	28 (78)	12 (33)
Nausea	12 (33)	2 (6)
Abnormal dreams	11 (31)	2 (6)
Affect labilitya	7 (19)	3 (8)
Insomnia	7 (19)	2 (6)
Headache	5 (14)	2 (6)
Gastroesophageal reflux disease	4 (11)	2 (6)
Abdominal pain	4 (11)	1 (3)
Nightmares	3 (8)	2 (6)
Sleep disorder	3 (8)	1 (3)
Weight gain	3 (8)	1 (3)
Vomiting	3 (8)	0
Constipation	3 (8)	0
Taste perversion	3 (8)	0
Fatigue	3 (8)	0
Depressed mood	2 (6)	1 (3)
Smell perversion	2 (6)	1 (3)
Gas	2 (6)	0
Sweat	2 (6)	0
Increased appetite	1 (3)	1 (3)
Dry mouth	1 (3)	0
Dizziness	1 (3)	0
Hot flush	1 (3)	0
Muscle pain	1 (3)	0

^aAffect lability, included irritability, mood swing, agitation, and anger.

AEs, adverse events.