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. 2011 Oct 28;118(25):6562–6571. doi: 10.1182/blood-2011-05-349084

Figure 1.

Figure 1

Enhanced proliferation of hematopoietic progenitor cells in Dmtf1−/− mice. BM-MNCs (A) or sorted KSLs (B) from WT, Dmtf1-KO, or Het mice were cultured with cytokines in methylcellulose medium for 10 days (n = 3) *P < .01 and **P < .05. (C) Representative dot plots showing MPPs (CD34+135+KSL), ST-HSCs (CD34+135−KSL), and LT-HSCs (CD34−135−KSL) in WT and Dmtf1-KO BM. (D) Quantification of the absolute number of KSLs, MPPs, ST-HSCs, and LT-HSCs and (G) quantification of the absolute number of progenitors (c-Kit+ and Sca1+) expressed as average ± SD per femur (n = 6). *P < .03 and *P < .05. (E) Absolute numbers of slamKSL (CD48−CD150+KSL) and (F) CD34− slamKSL expressed as average ± SD per femur (n = 7).