Table 2.
The Frequency of Detection and the Median Load of Herpesviruses in Blood and Semen Plasma Samples From HIV-1–Infected and HIV-Uninfected Men
| HIV-Uninfecteda |
HIV-1–Infecteda |
Pb |
||||
| Herpesvirus | Blood Plasma | Semen Plasma | Blood Plasma | Semen Plasma | Blood | Semen |
| HSV-2 | 0 | 0 | 0 | 4/50 (8); 2.1 (1.9–2.3) | NS | NS |
| EBV | 0 | 1/28 (3.5); 5.5 | 21/74 (28); 3.2 (2.7–3.6) | 28/50 (56); 3.5 (3.1–4.7) | <.001 | <.001 |
| CMV | 0 | 1/28 (3.5); 3.2 | 12/74 (16); 3.1 (2.9–3.4) | 35/50 (70); 5.3 (4.4–6.1) | <.001 | <.001 |
| HHV-6 | 0 | 3/28 (6); 3.7 (3.7–4.5) | 0 | 1/50 (2); 3.3 | NS | NS |
| HHV-7 | 0 | 3/28 (6); 3 (2.2–3.1) | 0 | 6/50 (12); 2.7 (2.3–3.1) | NS | NS |
| HHV-8 | 0 | 0 | 0 | 3/50 (6); 3.3 (3.1–3.5) | NS | NS |
Abbreviations: CMV, cytomegalovirus; EBV, Epstein-Barr virus; HHV, human herpesvirus; HIV, human immunodeficiency virus; HSV, herpes simplex virus; NS, not significant.
a
Data are presented as frequency of DNA detection (%); median DNA viral load (interquartile range), expressed as log10 copies/mL.
b
Significance of the difference in frequency of DNA detection between HIV-uninfected and HIV-1–infected individuals.