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. 2011 Dec 19;6(12):e29024. doi: 10.1371/journal.pone.0029024

Figure 9. In silico assessment of G3BP1 binding to RasGAP.

Figure 9

In silico docking assays were performed as described in the methods with the SH3 domain of RasGAP on either the G3BP1 NTF2-like domain (panel A) or sequence 190–233 of Ubp5, the yeast orthologue of USP10 (panel B). The 15 best interactions are presented in the figure. While the interactions of G3BP1 and USP10 were of similar nature (note the superposition of the USP10 structures in green), there was no preferred docking interaction between the SH3 domain of RasGAP and G3BP1.