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. 2011 Dec 19;6(12):e29144. doi: 10.1371/journal.pone.0029144

Table 2. Condensed chromatin area and chromatin textural contrast in 0.05 mM VPA- treated HeLa cells.

Treatment Sc% AAR
time (h) Drug X S Md X S Md
1 Untreated control 69.17 10.13 70.77a 1.27 0.09 1.26a
VPA 36.33 25.04 38.22b 1.40 0.17 1.37b
2 Untreated control 68.53 14.52 70.65a 1.25 0.08 1.24a
VPA 37.29 22.07 36.85b 1.44 0.16 1.42b
4 Untreated control 60.15 13.17 60.86a 1.36 0.14 1.35a
VPA 33.43 20.81 31.25b 1.40 0.15 1.38b
24 Untreated control 57.75 14.84 59.91a 1.35 0.14 1.32a
VPA 38.76 18.96 40.84b 1.40 0.11 1.39b
a,b

, The median values of the VPA group and the respective control for each treatment time differ significantly from each other at the P 0.05 level (Mann-Whitney test); AAR, average absorption ratio; Md, median; S, standard deviation; Sc %, relative condensed chromatin area; VPA, valproic acid; X, arithmetic mean; n, 200