Table 2. Condensed chromatin area and chromatin textural contrast in 0.05 mM VPA- treated HeLa cells.
Treatment | Sc% | AAR | |||||
time (h) | Drug | X | S | Md | X | S | Md |
1 | Untreated control | 69.17 | 10.13 | 70.77a | 1.27 | 0.09 | 1.26a |
VPA | 36.33 | 25.04 | 38.22b | 1.40 | 0.17 | 1.37b | |
2 | Untreated control | 68.53 | 14.52 | 70.65a | 1.25 | 0.08 | 1.24a |
VPA | 37.29 | 22.07 | 36.85b | 1.44 | 0.16 | 1.42b | |
4 | Untreated control | 60.15 | 13.17 | 60.86a | 1.36 | 0.14 | 1.35a |
VPA | 33.43 | 20.81 | 31.25b | 1.40 | 0.15 | 1.38b | |
24 | Untreated control | 57.75 | 14.84 | 59.91a | 1.35 | 0.14 | 1.32a |
VPA | 38.76 | 18.96 | 40.84b | 1.40 | 0.11 | 1.39b |
, The median values of the VPA group and the respective control for each treatment time differ significantly from each other at the P 0.05 level (Mann-Whitney test); AAR, average absorption ratio; Md, median; S, standard deviation; Sc %, relative condensed chromatin area; VPA, valproic acid; X, arithmetic mean; n, 200