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. 2011 Dec 19;6(12):e29431. doi: 10.1371/journal.pone.0029431

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Ihsan et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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The interaction model describes the percentage of the entropy (information gain) removed by each variable (main effect: represented by nodes) and by each pairwise combination of attributes (interaction effect: represented by connections). Attributes are selected on the basis of MDR results obtained in case of (A) Smokers and (B) Non smokers. Labels: Ex3: EPHX1 Tyr113His, Alc: alcohol consumption, Tbc: Tobacco chewing, SULT: SULT1A1 Arg213His, 2A: CYP1A1*2A, 2C: CYP1A1*2C, P1: GSTP1 Ile105Val.