Table 5. False positive report probability and odds ratio for best model of MDR analysis.
OR (95% CI) p value | OR = 1.5 | Prior Probability | OR = 2.0 | Prior Probability | |||||||||||
Power | 10−1 | 10−2 | 10−3 | 10−4 | 10−5 | 10−6 | Power | 10−1 | 10−2 | 10−3 | 10−4 | 10−5 | 10−6 | ||
Total Data Set Smk Ex3 Ex4 SULT | 4.93 (3.32–7.33) p < 0.0001 | 0.0001 | <10−4 | <10−4 | 0.001 | 0.015 | 0.131 | 0.131 | 0.0001 | <10−4 | <10−4 | <10−4 | <10−4 | <10−4 | <10−4 |
Smokers Tbc Ex3 SULT | 4.55 (2.69–7.69) p < 0.0001 | 0.0001 | 0.008 | 0.081 | 0.472 | 0.900 | 0.989 | 0.989 | 0.001 | <10−4 | 0.001 | 0.014 | 0.125 | 0.588 | 0.588 |
Non Smokers 2A P1 SULT | 7.32 (3.24–6.53) p < 0.0001 | 0.0001 | 0.180 | 0.708 | 0.961 | 0.996 | 1.00 | 1.00 | 0.001 | 0.016 | 0.155 | 0.650 | 0.949 | 0.995 | 0.995 |
Prior probabilities ranging from 0.1 to 10−6, with the estimated statistical power to detect an OR of 1.5 or 2.0 with α level equal to the observed p-value.
Bold type indicates the FPRP for the most likely prior probabilities i.e. a noteworthy association at the 0.2 FPRP.