Table 2.

Differentially methylated regions in the liver vs. cerebral cortex comparison

Genome Browser Coordinates	Gene Symbol	Distance to Gene	CpG Islands	Higher DNAm	%DNAm Diff.	p-value
Chr3: 164,013,013–164,018,139	Pck1	Inside	3	Cortex	44.3	0.0
Chr11: 80,333,032–80,335,418	Ahsg	Inside	2	Cortex	55.0	4.95E-06
Chr6: 7,208,313–7,211,263	Haao	5′ Overlap	1	Cortex	43.3	9.90E-06
Chr6: 123,596,462–123,598,885	Foxn3	Inside	1	Cortex	53.4	1.48E-05
Chr10: 87,543,661–87,546,156	Nr1d1	5′ Overlap	1	Liver	45.9	1.98E-05
Chr7: 127,669,312–127,672,145	Tymp	5′ Overlap	3	Cortex	49.1	2.47E-05
Chr16: 71,242,887–71,245,895	Tacc1	Inside	1	Liver	40.7	2.97E-05
Chr19: 39,107,530–39,109,768	Pmfbp1	252.7 kb 5′	1	Liver	57.6	3.46E-05
Chr19: 55,110,402–55,112,977	Egln1	Inside	1.4 kb	Liver	42.5	3.96E-05
Chr11: 80,328,977–80,330,696	Ahsg	5′ Overlap	2.9 kb	Cortex	56.3	4.45E-05
Chr5: 61,971,442–61,973,643	Mcart1	3.0 kb 5′	0.6 kb	Cortex	44.5	4.95E-05
Chr10: 45,223,909–45,225,954	Rnf187	Inside	1.0 kb	Liver	52.7	5.44E-05
Chr1: 246,606,435–246,608,736	Pik3ap1	Inside	1	Cortex	41.9	5.94E-05
Chr7: 135,726,079–135,727,791	Slc38a4	Inside	2	Cortex	53.9	6.43E-05
Chr6: 27,470,991–27,473,392	Ncoa1	Inside	0.2 kb	Liver	44.5	7.42E-05
Chr7: 27,505,278–27,507,777	Anks1b	5′ Overlap	1	Liver	50.6	7.92E-05
Chr2: 104,430,837–104,432,642	Pde7a	1.0 kb 5′	1	Liver	54.7	8.41E-05
Chr10: 56,586,885–56,588,600	Amac1	4.6 kb 5′	1	Liver	41.6	8.91E-05
Chr15: 33,195,773–33,197,808	Zfhx2	Inside	3	Liver	49.0	9.90E-05
Chr13: 50,023,990–50,025,760	Nr5a2	Inside	3.6 kb	Cortex	45.9	0.00010

Numbers in the CpG Islands column indicate either the number of CpG islands that overlap the DMR, or if zero, the distance to the closest CpG island. Due to the low number of samples for liver (N = 4), FDR values were not calculated. Gene names marked in bold indicate genes annotated in the UCSC Genome Browser only for the human and mouse, but presumed to exist in the rat.