Table 4.

Differentially methylated regions in the hippocampus vs. hypothalamus comparison

Genome Browser Coordinates	Gene Symbol	Distance to Gene	CpG Islands	Higher DNAm	%DNAm Diff.	p-value	FDR
Chr2: 224,889,643–224,894,609	Neurog2	1.1 kb 5′	2	Hippo	20.0	0.0	0.0
Chr17: 17,246,509–17,249,804	Msx2	3′ Overlap	2	Hippo	26.7	0.0	0.0
Chr17: 7,137,629–7,140,376	Ptch1	Inside	2	Hippo	27.2	0.0	0.0
Chr19: 38,428,600–38,432,412	Zfhx3	2.0 kb 5′	1.7 kb	Hippo	23.9	0.0	0.0
Chr4: 49,675,537–49,678,312	Cadps2	Inside	3	Hypo	33.7	0.0	0.0
Chr3: 163,466,175–163,469,441	Tcfap2c	3′ Overlap	1	Hypo	26.6	0.0	0.0
Chr1: 88,932,773–88,934,961	Tshz3	228.9 kb 5′	1	Hypo	35.9	1.73E-05	0.00953
Chr12: 40,871,330–40,873,237	Suds3	180.7 kb 3′	2	Hypo	35.4	1.73E-05	0.00953
Chr16: 36,321,272–36,323,521	Hand2	0.8 kb 3′	2.0 kb	Hippo	25.6	1.73E-05	0.00953
Chr12: 3,805,413–3,807,935	Kl	33.0 kb 5′	2	Hypo	23.4	1.73E-05	0.00953
Chr1: 266,014,210–266,016,505	Emx2	2.9 kb 3′	1	Hippo	22.4	1.73E-05	0.00953
Chr5: 146,036,109–146,037,543	Psmb2	51.7 kb 5′	1	Hypo	40.6	2.02E-05	0.00953
Chr3: 163,455,717–163,458,236	Tcfap2c	1.0 kb 5′	5	Hippo	23.4	2.02E-05	0.00953
Chr3: 38,868,010–38,869,983	Nr4a2	Inside	3	Hippo	31.6	2.02E-05	0.00953
Chr18: 74,158,604–74,160,874	St8sia5	3.1 kb 5′	1.3 kb	Hypo	28.5	2.02E-05	0.00953
Chr4: 183,097,328–183,100,393	Ifltd1	19.7 kb 5′	0.9 kb	Hypo	19.8	2.60E-05	0.01134
Chr11: 11,892,675–11,894,274	Robo1	172.0 kb 3′	1	Hypo	34.2	2.89E-05	0.01134
Chr6: 132,389,251–132,392,858	Bcl11b	4.7 kb 5′	2	Hypo	14.8	2.89E-05	0.01134
Chr3: 91,116,249–91,118,038	Pax6	9.6 kb 5′	0.5 kb	Hippo	27.6	3.18E-05	0.01182
Chr20: 25,980,822–25,982,535	Ctnna3	Inside	4	Hypo	33.2	3.75E-05	0.01327

Numbers in the CpG Islands column indicate either the number of CpG islands that overlap the DMR, or if zero, the distance to the closest CpG island. Gene names marked in bold indicate genes annotated in the UCSC Genome Browser only for the human and mouse, but presumed to exist in the rat.