Table 6.

Differentially methylated regions in the cerebral cortex vs. hypothalamus comparison

Genome Browser Coordinates	Gene Symbol	Distance to Gene	CpG Islands	Higher DNAm	%DNAm Diff.	p-value	FDR
Chr2: 224,889,548–224,894,316	Neurog2	1.4 kb 5′	2	Cortex	19.2	0.0	0.0
Chr14: 100,710,575–100,715,363	Spred2	Inside	1.0 kb	Hypo	24.2	0.0	0.0
Chr6: 130,607,715–130,610,889	Vrk1	358.4 kb 3′	2	Hypo	31.2	0.0	0.0
Chr18: 74,158,499–74,161,968	St8sia5	2.0 kb 5′	0.3 kb	Hypo	26.5	0.0	0.0
Chr17: 17,246,672–17,249,804	Msx2	3′ Overlap	2	Cortex	24.6	0.0	0.0
Chr17: 7,137,629–7,140,331	Ptch1	Inside	2	Cortex	26.9	0.0	0.0
Chr1: 23,780,028–23,782,977	Sgk1	270.9 kb 5′	2	Hypo	23.4	0.0	0.0
Chr12: 6,564,480–6,566,824	Rpl35a	7.3 kb 3′	1	Hypo	33.0	0.0	0.0
Chr19: 38,428,535–38,432,257	Zfhx3	2.6 kb 5′	1.9 kb	Cortex	20.7	3.131E-06	0.00267
Chr4: 8,969,556–8,972,220	Lrrc17	Inside	0.3 kb	Hypo	25.1	6.263E-06	0.00400
Chr2: 177,162,376–177,164,873	Fdps	77.9 kb 3′	1	Hypo	26.4	6.263E-06	0.00400
Chr2: 35,033,638–35,035,978	Sgtb	Inside	1	Hypo	28.5	9.394E-06	0.00400
Chr8: 74,211,291–74,213,781	Foxb1	8.4 kb 5′	1	Hypo	19.9	9.394E-06	0.00400
Chr1: 95,646,663–95,648,875	Slc17a7	Inside	0.1 kb	Hypo	29.9	9.394E-06	0.00400
Chr3: 38,867,965–38,870,218	Nr4a2	Inside	4	Cortex	31.7	9.394E-06	0.00400
Chr10: 31,085,071–31,088,230	Thg1l	0.7 kb 3′	2	Hypo	25.6	9.394E-06	0.00400
Chr1: 232,594,738–232,597,692	RGD1310039	Inside	0.7 kb	Hypo	23.2	9.394E-06	0.00400
Chr2: 83,442,269–83,445,183	Ankrd33b	Inside	0.3 kb	Hypo	20.1	1.253E-05	0.00400
Chr17: 82,655,805–82,658,235	Cugbp2	50.1 kb 5′	10.7 kb	Hypo	24.4	1.253E-05	0.00400
Chr13: 44,182,429–44,185,020	Rassf5	Inside	1.1 kb	Hypo	21.8	1.253E-05	0.00400

Numbers in the CpG Islands column indicate either the number of CpG islands that overlap the DMR, or if zero, the distance to the closest CpG island. Gene names marked in bold indicate genes annotated in the UCSC Genome Browser only for the human and mouse, but presumed to exist in the rat.