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The intermittent access to 10% (v/v) alcohol in a two-bottle free choice drinking paradigm produces a robust escalation in alcohol intake. The values are expressed as mean ± SEM alcohol intake (g/kg/day) at each drinking session. Statistical difference from the first drinking session: In the intermittent access group (N=8) *p<0.05 and **p<0.01; in the continuous access group (N=8) ##p<0.01.
